Fig 1: IHS inhibits JAK/STAT3/IL6 signaling in ApcMin/+ mice. IHS decreased the protein levels of IL-5, IL-6, IL-10, P-JAK1/JAK1, P-JAK2/JAK2, P-STAT3/STAT3, and P-STAT5/STAT5 and increased the level of P-STAT1/STAT1, as detected through Western blotting of tumor (A) and spleen tissue (B) of ApcMin/+ mice. IHS decreased the levels of (C) IL-5, (D) IL-6, and (E) IL-10 in tumor and spleen tissue of ApcMin/+ mice, as detecting through ELISA. Data were analyzed using a one-way ANOVA and are shown as means ± SEM. * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. vehicle-treated group.
Supplier Page from Proteintech Group Inc for Mouse IL-5 ELISA Kit